University of the West of England

MODULE SPECIFICATION

Code: USSJ6F-30-M Title: CELLULAR PATHOLOGY Version: 4

Level: M UWE credit rating: 30 ECTS credit rating: 15

Module type: STANDARD

Owning Faculty: Applied Sciences Field: Natural & Life Sciences

Valid from: September 2006 Discontinued from:

Pre-requisites: NONE

Co-requisites: NONE

Excluded combinations: NONE

Learning outcomes:

      • discuss the effects of histological techniques on cells and tissues.

      • critically evaluate developing methodologies in cellular pathology.

      • critically evaluate the role of cellular pathology in the investigation of selected diseases.

      • discuss at an advanced level the pathology of selected disease processes.

      • discuss the ways in which tissues can be prepared for microscopic examination.

      • critically evaluate selected histological, histochemical, immunoytochmical and molecular

      • techniques and their respective roles in the diagnostic process.

Syllabus outline:

    Cell and tissue stabilisation. Preparative processes in cellular pathology. Microscopy in cellular pathology including the role of the electron microscope. The theory of stain action. The histochemistry of carbohydrates, lipids and proteins including enzymes. Immunocytochemistry. Molecular biology in cellular pathology.

Quantitation. Quality control in cellular pathology

    Tissue pigmentation. Inorganic constituents of tissue, both endogenous and exogenous. The cellular pathology of infection by selected micro-organisms. Cytopathology in diagnosis and as a screening process.

Systemic diseases e g Amyloidosis.

    Systemic pathology of selected organs and tissues e g the urinary system, the central and peripheral nervous systems, muscle, haemopoietic tissues and the skeleton.

Teaching and learning methods:

    The module will be delivered as a series of key-note lectures on topics in cellular pathology. The lectures will be designed to integrate the scientific aspects of cellular pathology with aspects of systemic pathology. The lecture sessions will provide a framework which will act as a focus for self learning by students. Seminars will be used to develop communication skills.

    Analytical skills of the students will be developed by the use of investigative practicals. The practicals will be undertaken by small groups working together in problem solving exercises.

Students will also be encouraged to explore and directed towards appropriate web sites and laboratory based interactive CD-roms.

Reading Strategy

All students will be encouraged to make full use of the print and electronic resources available to them through membership of the University. These include a range of electronic journals and a wide variety of resources available through web sites and information gateways. The University Library’s web pages provide access to subject relevant resources and services, and to the library catalogue. Many resources can be accessed remotely. Students will be presented with opportunities within the curriculum to develop their information retrieval and evaluation skills in order to identify such resources effectively.

This guidance will be available either in the module handbook, via the module information on UWEonline or through any other vehicle deemed appropriate by the module/programme leaders.

Pathology; Stevens and Lowe; Mosby; 1995

    Theory and Practice of Histological Techniques; Bancort, J D and Stevens, A (Eds); Churchill Livingstone; 2001

Principles and practice of neuropathology; Nelson, Paish, Schochet; Mosby; 1994

Laboratory histopathology; Woods, Ellis; Churchill Livingstone; 1995

Pathology; Rubin and Farber; Lippincott-Raven, 1999

    Oxford textbook of pathology Vols 1,2a & 2b; Mcgee, Isaacson, Wright; Oxford Medical Publications; 1992

Skeletal muscle pathology; Mastaglia, Walton; Churchill Livingstone; 1992

Diagnostic histopathology of tumorus; Fletcher; Churchill Livingstone; 1995

Essential cell biology; Alberts, Bray, Johnson, Lewis, Raff, Roberts, Walter; Garland; 1997

Resin microscopy and on section immunocytochemistry; Newman, Hobot; Springer; 1993

Immunogold-silver staining; Hyat; CRC press; 1996;

Blood; Palister; Butterworth; 1996

JOURNALS

Histochemistry and Cytochemistry

Histopathology

Histochemical Journal

Journal of Clinical Pathology

Journal of Pathology

Assessment

Weighting between components A and B (standard modules only) A: 50% B: 50%

ATTEMPT 1

First Assessment Opportunity

Component A Element weighting

EX3

Examination (3 Hours)

1

     
     

Component B

Description of each element Element weighting

ES1

Essay

1

   

     

Second Assessment Opportunity (further attendance at taught classes) No

Component A

Description of each element Element weighting

EX3

Examination (3 Hours)

1

     
     

Component B

Description of each element Element weighting

ES1

Essay

1

     
     

SECOND (OR SUBSEQUENT) ATTEMPT Attendance at taught classes. Yes

Specification confirmed by …………………………………………………Date ……………………………

(Associate Dean/Programme Director)

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