University of the
West of England
MODULE SPECIFICATION
Code: USSJJX-30-M Title: Applied Genomics (M)
Level: UWE credit rating: ECTS credit rating:
Owning Faculty: Health and Life Sciences Field:
Faculty Committee approval: Q&S Committee (School of Life Sciences) Date: Summer 2009
Approved for Delivery by: N/A
Valid from: September 2009 Discontinued from:
Pre-requisites:
Co-requisites:
Entry requirements:
Excluded combinations:
Learning outcomes:
- critically discuss current approaches to genome analysis;
- critically discuss the concept of ‘model’ genomes, their importance and evolution;
- review in detail the scope of bioinformatics;
- critically discuss information networks, protein and genome resources;
- study alignment techniques indepth;
- assess analysis methods underpinning secondary databases searching for protein sequences;
- select and use appropriate bioinformatic ‘tools’;
- critically assess, present and discuss primary reference source material.
Syllabus outline:
In this module students will study the current state of genome analysis. This will include the study of model genomes including their structure and organisation, patterns, transcriptomes and proteomes, and their molecular evolution. The module also looks at functional genomics including expression analysis, transcriptomics and proteomics. The module will also cover theoretical and practical application of bioinformatics.
Teaching and learning methods:
The module will be delivered as mix of lectures and data analysis tutorials, together with student centred case study and research paper presentation.
Reading Strategy:
All students will be encouraged to make full use of the print and electronic resources available to them through membership of the University. These include a range of electronic journals and a wide variety of resources available through web sites and information gateways. The University Library’s web pages provide access to subject relevant resources and services, and to the library catalogue. Many resources can be accessed remotely. Students will be presented with opportunities within the curriculum to develop their information retrieval and evaluation skills in order to identify such resources effectively.
Any essential reading will be indicated clearly, along with the method for accessing it, e.g. students may be expected to purchase a set text, be given or sold a print study pack or be referred to texts that are available electronically, etc. This guidance will be available either in the module handbook, via the module information on Blackboard or through any other vehicle deemed appropriate by the module/programme leaders.
If further reading is expected, this will be indicated clearly. If specific texts are listed, a clear indication will be given regarding how to access them and, if appropriate, students will be given guidance on how to identify relevant sources for themselves, e.g. through use of bibliographical databases.
Indicative Reading List:
The following list is offered to provide validation panels/accrediting bodies with an indication of the type and level of information students may be expected to consult. As such, its currency may wane during the life span of the module specification. However, as indicated above, CURRENT advice on readings will be available via other more frequently updated mechanisms.
•Primrose SB & Twyman RM. Principles of Genome Analysis & Genomics. 2003. Blackwell.
•Brown TA. Genomes 3. 2006. Bios.
•Lesk AM. 2007. Introduction to Genomics. Oxford University press.
•Lesk AM. 2008. Introduction to bioinformatics (3rd edn.). Oxford University press.
•Westhead DR, Parish JH & Twyman. 2002. Instant Notes; Bioinformatics. Bios.
•Russell PJ. iGenetics – A Molecular Approach. 2006. Pearson Education.
•Brown TA. Gene Cloning and DNA Analysis (5th edn.) 2006. Blackwell Science.
•Dale JW & vonSchantz M. From Genes to Genomes. 2002. Wiley
•Plus appropriate use of relevant primary reference journals and www based resources
Assessment:
Weighting between components A and B (standard modules only) A: 50% B: 50%
ATTEMPT 1
First Assessment Opportunity
Component A (controlled) Element weighting
EX3 |
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Component B
Description of each element Element weighting
CW1 |
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CW2 |
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Second Assessment Opportunity (further attendance at taught classes )
Component A
Description of each element Element weighting
EX3 |
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Component B
Description of each element Element weighting
CW1 |
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SECOND (OR SUBSEQUENT) ATTEMPT Attendance at taught classes .
Specification confirmed by …………………………………………………Date ……………………………
(Associate Dean/Programme Director)